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Decreased proteasomal cleavage at nitrotyrosine sites in proteins and peptides

Removal of moderately oxidized proteins is mainly carried out by the proteasome, while highly modified proteins are no longer degradable. However, in the case of proteins modified by nitration of tyrosine residues to 3-nitrotyrosine (NO(2)Y), the role of the proteasome remains to be established. For...

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Detalles Bibliográficos
Autores principales:	Ott, Christiane, Tomasina, Florencia, Campolo, Nicolás, Bartesaghi, Silvina, Mastrogiovanni, Mauricio, Leyva, Alejandro, Batthyány, Carlos, Meinl, Walter, Grune, Tilman, Radi, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403764/ https://www.ncbi.nlm.nih.gov/pubmed/34455147 http://dx.doi.org/10.1016/j.redox.2021.102106

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