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Fused in sarcoma regulates DNA replication timing and kinetics
Fused in sarcoma (FUS) encodes an RNA-binding protein with diverse roles in transcriptional activation and RNA splicing. While oncogenic fusions of FUS and transcription factor DNA-binding domains are associated with soft tissue sarcomas, dominant mutations in FUS can cause amyotrophic lateral scler...
Autores principales: | Jia, Weiyan, Kim, Sang Hwa, Scalf, Mark A., Tonzi, Peter, Millikin, Robert J., Guns, William M., Liu, Lu, Mastrocola, Adam S., Smith, Lloyd M., Huang, Tony T., Tibbetts, Randal S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403768/ https://www.ncbi.nlm.nih.gov/pubmed/34375640 http://dx.doi.org/10.1016/j.jbc.2021.101049 |
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