Cargando…

Fused in sarcoma regulates DNA replication timing and kinetics

Fused in sarcoma (FUS) encodes an RNA-binding protein with diverse roles in transcriptional activation and RNA splicing. While oncogenic fusions of FUS and transcription factor DNA-binding domains are associated with soft tissue sarcomas, dominant mutations in FUS can cause amyotrophic lateral scler...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Weiyan, Kim, Sang Hwa, Scalf, Mark A., Tonzi, Peter, Millikin, Robert J., Guns, William M., Liu, Lu, Mastrocola, Adam S., Smith, Lloyd M., Huang, Tony T., Tibbetts, Randal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403768/
https://www.ncbi.nlm.nih.gov/pubmed/34375640
http://dx.doi.org/10.1016/j.jbc.2021.101049

Ejemplares similares