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Engineering genetic devices for in vivo control of therapeutic T cell activity triggered by the dietary molecule resveratrol
Chimeric antigen receptor (CAR)–engineered T cell therapies have been recognized as powerful strategies in cancer immunotherapy; however, the clinical application of CAR-T is currently constrained by severe adverse effects in patients, caused by excessive cytotoxic activity and poor T cell control....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403971/ https://www.ncbi.nlm.nih.gov/pubmed/34404729 http://dx.doi.org/10.1073/pnas.2106612118 |