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Synthesis of novel calcium channel blockers with ACE2 inhibition and dual antihypertensive/anti-inflammatory effects: A possible therapeutic tool for COVID-19

Hypertension has been recognized as one of the most frequent comorbidities and risk factors for the seriousness and adverse consequences in COVID-19 patients. 3,4-dihydropyrimidin-2(1H) ones have attracted researchers to be synthesized via Beginilli reaction and evaluate their antihypertensive activ...

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Detalles Bibliográficos
Autores principales:	Mahgoub, Shahenda, Kotb El-Sayed, Mohamed-I, El-Shehry, Mohamed F., Mohamed Awad, Samir, Mansour, Yara E., Fatahala, Samar S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403975/ https://www.ncbi.nlm.nih.gov/pubmed/34474305 http://dx.doi.org/10.1016/j.bioorg.2021.105272

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