Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity

[Image: see text] Modern adjuvants for vaccine formulations are immunostimulating agents whose action is based on the activation of pattern recognition receptors (PRRs) by well-defined ligands to boost innate and adaptive immune responses. Monophosphoryl lipid A (MPLA), a detoxified analogue of lipi...

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Detalles Bibliográficos
Autores principales: Facchini, Fabio A., Minotti, Alberto, Luraghi, Andrea, Romerio, Alessio, Gotri, Nicole, Matamoros-Recio, Alejandra, Iannucci, Andrea, Palmer, Charys, Wang, Guanbo, Ingram, Rebecca, Martin-Santamaria, Sonsoles, Pirianov, Grisha, De Andrea, Marco, Valvano, Miguel A., Peri, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404200/
https://www.ncbi.nlm.nih.gov/pubmed/34382796
http://dx.doi.org/10.1021/acs.jmedchem.1c00896

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