Cargando…

Landscape of IDH1/2 mutations in Chinese patients with solid tumors: A pan‐cancer analysis

BACKGROUND: Isocitrate dehydrogenase (IDH) is an enzyme family involved in cell aerobic metabolism of tricarboxylic acid cycle. However, the landscape of IDH mutations in pan‐cancer has not been fully characterized. METHODS: Tissue or blood samples were subjected to next‐generation sequencing (NGS)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Dong, Zhang, Junling, Yuan, Kai, Zhao, Jing, Zhao, Zhengyi, Cui, Longgang, Zhang, Yuzi, Wang, Guoqiang, Cai, Shangli, Bai, Yuezong, Li, Wei, Huang, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Genetics and Genomic Medicine Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404228/ https://www.ncbi.nlm.nih.gov/pubmed/34145795 http://dx.doi.org/10.1002/mgg3.1697

Ejemplares similares

Efficacy and safety of PD-1/PD-L1 inhibitors plus nab-paclitaxel for patients with non-small cell lung cancer who have progressed after platinum-based chemotherapy
por: Zhang, Fan, et al.
Publicado: (2020)

Association between DNA damage repair gene somatic mutations and immune‐related gene expression in ovarian cancer
por: Tian, Wenjuan, et al.
Publicado: (2020)

Landscape of FGF/FGFR Alterations in 12,372 Chinese Cancer Patients
por: Zuo, Wei, et al.
Publicado: (2020)

Redefine Hyperprogressive Disease During Treatment With Immune-Checkpoint Inhibitors in Patients With Gastrointestinal Cancer
por: Wang, Zhenghang, et al.
Publicado: (2021)

Molecular Landscape of ERBB2 Alterations in 14,956 Solid Tumors
por: Wang, Hao, et al.
Publicado: (2022)

Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition
por: Pacheco-Moreno, Alba, et al.
Publicado: (2021)

New insights into the novel sequences of the chicken pan-genome by liquid chip
por: Wang, Fei, et al.
Publicado: (2022)

The regulatory landscape of retinoblastoma: a pathway analysis perspective
por: Gómez-Romero, Laura, et al.
Publicado: (2022)

The landscape of m(1)A modification and its posttranscriptional regulatory functions in primary neurons
por: Zhang, Chi, et al.
Publicado: (2023)

Hybrid Capture-based Genomic Profiling of Circulating Tumor DNA From Patients With Advanced Ovarian Cancer
por: Shen, Wenbin, et al.
Publicado: (2021)

A tailored next‐generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas
por: Higa, Nayuta, et al.
Publicado: (2020)

Correction: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons
por: Zhang, Chi, et al.
Publicado: (2023)

Development and validation of a brief screening instrument for psychosocial risk associated with genetic testing: a pan-Canadian cohort study
por: Esplen, Mary Jane, et al.
Publicado: (2013)

Extensive impact of low-frequency variants on the phenotypic landscape at population-scale
por: Fournier, Téo, et al.
Publicado: (2019)

Arrayed CRISPRi and quantitative imaging describe the morphotypic landscape of essential mycobacterial genes
por: de Wet, Timothy J, et al.
Publicado: (2020)

IDH1: Linking Metabolism and Epigenetics
por: Raineri, Silvia, et al.
Publicado: (2018)

Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancer
por: Hu, Hanyang, et al.
Publicado: (2017)

Integrative pan-cancer landscape of MMS22L and its potential role in hepatocellular carcinoma
por: Guo, Zhiting, et al.
Publicado: (2022)

The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
por: Sanchez-Contreras, Monica, et al.
Publicado: (2023)

Role of simian virus 40 in cancer incidence in solid organ transplant patients
por: Paracchini, V, et al.
Publicado: (2006)

Anti-PD-1 Therapy plus Chemotherapy and/or Bevacizumab as Second Line or later Treatment for Patients with Advanced Non-Small Cell Lung Cancer
por: Zhang, Fan, et al.
Publicado: (2020)

Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)
por: Liu, Dan, et al.
Publicado: (2022)

Forensic efficiency estimate and phylogenetic analysis for Chinese Kyrgyz ethnic group revealed by a panel of 21 short tandem repeats
por: Guo, Yuxin, et al.
Publicado: (2018)

Multi-locus genomic signatures of local adaptation to snow across the landscape in California populations of a willow leaf beetle
por: Keller, Abigail G., et al.
Publicado: (2023)

Oncogenic signaling pathway dysregulation landscape reveals the role of pathways at multiple omics levels in pan-cancer
por: Wang, Na, et al.
Publicado: (2022)

Multi-omics analysis reveals a molecular landscape of the early recurrence and early metastasis in pan-cancer
por: He, Dan-ni, et al.
Publicado: (2023)

Comprehensive Genomic Landscape in Chinese Clear Cell Renal Cell Carcinoma Patients
por: Huang, Jiwei, et al.
Publicado: (2021)

Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks
por: Bing, XiaoLi, et al.
Publicado: (2017)

Disruption of PIKFYVE causes congenital cataract in human and zebrafish
por: Mei, Shaoyi, et al.
Publicado: (2022)

Association of IL-10 and IL-10RA single nucleotide polymorphisms with the responsiveness to HBV vaccination in Chinese infants of HBsAg(+)/HBeAg(−) mothers: a nested case–control study
por: Wen, Simin, et al.
Publicado: (2018)

Replication study of SNP associations for colorectal cancer in Hong Kong Chinese
por: Ho, J W, et al.
Publicado: (2011)

Pan-cancer analysis of prognostic and immunological role of DTYMK in human tumors
por: Zhao, Huihui, et al.
Publicado: (2022)

Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours
por: Singh, R R, et al.
Publicado: (2014)

Analysis and identification of the necroptosis landscape on therapy and prognosis in bladder cancer
por: Zhao, Zihan, et al.
Publicado: (2022)

Comprehensive insights into the genetic background of Chinese populations using Y chromosome markers
por: Li, Jienan, et al.
Publicado: (2023)

Genetic diversity and breed identification of Chinese and Vietnamese local chicken breeds based on microsatellite analysis
por: Zhuang, Zhong, et al.
Publicado: (2023)

Human germline and pan-cancer variomes and their distinct functional profiles
por: Pan, Yang, et al.
Publicado: (2014)

Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes
por: Zhang, Xinyan, et al.
Publicado: (2020)

Global translational landscape of the Candida albicans morphological transition
por: Mundodi, Vasanthakrishna, et al.
Publicado: (2020)

Genomic and Transcriptomic Landscape of Tumor Clonal Evolution in Cholangiocarcinoma
por: Chen, Geng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g98do9amuokj00psv44hhda9k5