Conifer: clonal tree inference for tumor heterogeneity with single-cell and bulk sequencing data

BACKGROUND: Genetic heterogeneity of a cancer tumor that develops during clonal evolution is one of the reasons for cancer treatment failure, by increasing the chance of drug resistance. Clones are cell populations with different genotypes, resulting from differences in somatic mutations that occur...

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Detalles Bibliográficos
Autores principales: Baghaarabani, Leila, Goliaei, Sama, Foroughmand-Araabi, Mohammad-Hadi, Shariatpanahi, Seyed Peyman, Goliaei, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404257/
https://www.ncbi.nlm.nih.gov/pubmed/34461827
http://dx.doi.org/10.1186/s12859-021-04338-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404257/
https://www.ncbi.nlm.nih.gov/pubmed/34461827
http://dx.doi.org/10.1186/s12859-021-04338-7

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