Microarray analysis of ductal carcinoma in situ samples obtained by puncture from surgical resection specimens

OBJECTIVE: The incidence of ductal carcinoma in situ (DCIS) is increasing due to more widespread mammographic screening. DCIS, the earliest form of breast cancer, is non-invasive at the time of detection. If DCIS tissues are left undetected or untreated, it can spread to the surrounding breast tissu...

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Detalles Bibliográficos
Autores principales: Jikuzono, Tomoo, Manabe, Eriko, Kure, Shoko, Akasu, Haruki, Ishikawa, Tomoko, Fujiwara, Yoko, Makita, Masujiro, Ishibashi, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Data Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404306/
https://www.ncbi.nlm.nih.gov/pubmed/34461994
http://dx.doi.org/10.1186/s13104-021-05760-z
Descripción
Sumario:OBJECTIVE: The incidence of ductal carcinoma in situ (DCIS) is increasing due to more widespread mammographic screening. DCIS, the earliest form of breast cancer, is non-invasive at the time of detection. If DCIS tissues are left undetected or untreated, it can spread to the surrounding breast tissue. Thus, surgical resection is the standard treatment. Understanding the mechanism underlying the non-invasive property of DCIS could lead to more appropriate medical treatments, including nonsurgical options. DATA DESCRIPTION: We conducted a microarray-based genome-wide transcriptome analysis using DCIS specimens obtained by puncture from surgical specimens immediately after surgery.

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