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A validated generally applicable approach using the systematic assessment of disease modules by GWAS reveals a multi-omic module strongly associated with risk factors in multiple sclerosis

BACKGROUND: There exist few, if any, practical guidelines for predictive and falsifiable multi-omic data integration that systematically integrate existing knowledge. Disease modules are popular concepts for interpreting genome-wide studies in medicine but have so far not been systematically evaluat...

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Detalles Bibliográficos
Autores principales:	Badam, Tejaswi V. S., de Weerd, Hendrik A., Martínez-Enguita, David, Olsson, Tomas, Alfredsson, Lars, Kockum, Ingrid, Jagodic, Maja, Lubovac-Pilav, Zelmina, Gustafsson, Mika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404328/ https://www.ncbi.nlm.nih.gov/pubmed/34461822 http://dx.doi.org/10.1186/s12864-021-07935-1

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