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RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization
Zygotes require two accurate sets of parental chromosomes, one each from the mother and the father, to undergo normal embryogenesis. However, upon egg–sperm fusion in vertebrates, the zygote has three sets of chromosomes, one from the sperm and two from the egg. The zygote therefore eliminates one s...
Autores principales: | Mori, Masashi, Yao, Tatsuma, Mishina, Tappei, Endoh, Hiromi, Tanaka, Masahito, Yonezawa, Nao, Shimamoto, Yuta, Yonemura, Shigenobu, Yamagata, Kazuo, Kitajima, Tomoya S., Ikawa, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404465/ https://www.ncbi.nlm.nih.gov/pubmed/34424312 http://dx.doi.org/10.1083/jcb.202012001 |
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