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A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404560/ https://www.ncbi.nlm.nih.gov/pubmed/34497690 |
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author | Bahrizadeh, Farid Lisar, Hamidreza Azimi Naderi, Noushin Jalayer |
author_facet | Bahrizadeh, Farid Lisar, Hamidreza Azimi Naderi, Noushin Jalayer |
author_sort | Bahrizadeh, Farid |
collection | PubMed |
description | BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The aim was to determine the osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder on rat calvaria. MATERIALS AND METHODS: The study was experimental. Thirty-six male albino rats of the Wistar strain were included in the study. The 5 mm surgical defects were created on calvarias and filled with allograft bone material and covered by R. kutum swim bladder (Group I), bovine derived pericardial membrane (Group II) and without membrane cover (Group III).The specimen were euthanized after 3, 5 and 8 weeks. The surrounding connective tissue was evaluated in term of osseous formation. Kruskal–Wallis, Univariant analysis of variance, and post hoc tests were used for statistical analysis. The P < 0.05 was considered statistically significant. RESULTS: A significant differences between groups in terms of osseous formation (P = 0.001) was noted. The difference of osseous formation was significantly higher in 5 and 8 weeks than 3 weeks after operation in all groups (P = 0.03 and P = 0.006, respectively). The osseous formation in Group I and II were significantly higher than Group III (P = 0.023 and P = 0.001). CONCLUSION: The R. kutum swim bladder had osteogenic effect on rat calvaria. R. kutum swim bladder can be a new source in natural derived collagen membrane in GBR. |
format | Online Article Text |
id | pubmed-8404560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-84045602021-09-07 A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria Bahrizadeh, Farid Lisar, Hamidreza Azimi Naderi, Noushin Jalayer Dent Res J (Isfahan) Original Article BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The aim was to determine the osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder on rat calvaria. MATERIALS AND METHODS: The study was experimental. Thirty-six male albino rats of the Wistar strain were included in the study. The 5 mm surgical defects were created on calvarias and filled with allograft bone material and covered by R. kutum swim bladder (Group I), bovine derived pericardial membrane (Group II) and without membrane cover (Group III).The specimen were euthanized after 3, 5 and 8 weeks. The surrounding connective tissue was evaluated in term of osseous formation. Kruskal–Wallis, Univariant analysis of variance, and post hoc tests were used for statistical analysis. The P < 0.05 was considered statistically significant. RESULTS: A significant differences between groups in terms of osseous formation (P = 0.001) was noted. The difference of osseous formation was significantly higher in 5 and 8 weeks than 3 weeks after operation in all groups (P = 0.03 and P = 0.006, respectively). The osseous formation in Group I and II were significantly higher than Group III (P = 0.023 and P = 0.001). CONCLUSION: The R. kutum swim bladder had osteogenic effect on rat calvaria. R. kutum swim bladder can be a new source in natural derived collagen membrane in GBR. Wolters Kluwer - Medknow 2021-07-19 /pmc/articles/PMC8404560/ /pubmed/34497690 Text en Copyright: © 2021 Dental Research Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Bahrizadeh, Farid Lisar, Hamidreza Azimi Naderi, Noushin Jalayer A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title | A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title_full | A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title_fullStr | A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title_full_unstemmed | A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title_short | A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria |
title_sort | survey on osteogenic effect of collagen-membrane derived from rutilus kutum swim bladder in rat calvaria |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404560/ https://www.ncbi.nlm.nih.gov/pubmed/34497690 |
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