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A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria

BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The a...

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Autores principales: Bahrizadeh, Farid, Lisar, Hamidreza Azimi, Naderi, Noushin Jalayer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404560/
https://www.ncbi.nlm.nih.gov/pubmed/34497690
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author Bahrizadeh, Farid
Lisar, Hamidreza Azimi
Naderi, Noushin Jalayer
author_facet Bahrizadeh, Farid
Lisar, Hamidreza Azimi
Naderi, Noushin Jalayer
author_sort Bahrizadeh, Farid
collection PubMed
description BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The aim was to determine the osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder on rat calvaria. MATERIALS AND METHODS: The study was experimental. Thirty-six male albino rats of the Wistar strain were included in the study. The 5 mm surgical defects were created on calvarias and filled with allograft bone material and covered by R. kutum swim bladder (Group I), bovine derived pericardial membrane (Group II) and without membrane cover (Group III).The specimen were euthanized after 3, 5 and 8 weeks. The surrounding connective tissue was evaluated in term of osseous formation. Kruskal–Wallis, Univariant analysis of variance, and post hoc tests were used for statistical analysis. The P < 0.05 was considered statistically significant. RESULTS: A significant differences between groups in terms of osseous formation (P = 0.001) was noted. The difference of osseous formation was significantly higher in 5 and 8 weeks than 3 weeks after operation in all groups (P = 0.03 and P = 0.006, respectively). The osseous formation in Group I and II were significantly higher than Group III (P = 0.023 and P = 0.001). CONCLUSION: The R. kutum swim bladder had osteogenic effect on rat calvaria. R. kutum swim bladder can be a new source in natural derived collagen membrane in GBR.
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spelling pubmed-84045602021-09-07 A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria Bahrizadeh, Farid Lisar, Hamidreza Azimi Naderi, Noushin Jalayer Dent Res J (Isfahan) Original Article BACKGROUND: The collagen membrane which obtained from bovine pericardium and human skin in Guided Bone Regeneration (GBR) is costly and may even cause transmission of diseases. Replacing conventional collagen membranes with a more easily accessible and cheaper ones will have economic benefits. The aim was to determine the osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder on rat calvaria. MATERIALS AND METHODS: The study was experimental. Thirty-six male albino rats of the Wistar strain were included in the study. The 5 mm surgical defects were created on calvarias and filled with allograft bone material and covered by R. kutum swim bladder (Group I), bovine derived pericardial membrane (Group II) and without membrane cover (Group III).The specimen were euthanized after 3, 5 and 8 weeks. The surrounding connective tissue was evaluated in term of osseous formation. Kruskal–Wallis, Univariant analysis of variance, and post hoc tests were used for statistical analysis. The P < 0.05 was considered statistically significant. RESULTS: A significant differences between groups in terms of osseous formation (P = 0.001) was noted. The difference of osseous formation was significantly higher in 5 and 8 weeks than 3 weeks after operation in all groups (P = 0.03 and P = 0.006, respectively). The osseous formation in Group I and II were significantly higher than Group III (P = 0.023 and P = 0.001). CONCLUSION: The R. kutum swim bladder had osteogenic effect on rat calvaria. R. kutum swim bladder can be a new source in natural derived collagen membrane in GBR. Wolters Kluwer - Medknow 2021-07-19 /pmc/articles/PMC8404560/ /pubmed/34497690 Text en Copyright: © 2021 Dental Research Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Bahrizadeh, Farid
Lisar, Hamidreza Azimi
Naderi, Noushin Jalayer
A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title_full A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title_fullStr A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title_full_unstemmed A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title_short A survey on osteogenic effect of collagen-membrane derived from Rutilus kutum swim bladder in rat calvaria
title_sort survey on osteogenic effect of collagen-membrane derived from rutilus kutum swim bladder in rat calvaria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404560/
https://www.ncbi.nlm.nih.gov/pubmed/34497690
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