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Corticosteroid injection treatment for dactylitis in psoriatic arthritis
Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404638/ https://www.ncbi.nlm.nih.gov/pubmed/34471429 http://dx.doi.org/10.1177/1759720X211041864 |
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author | Carriero, Antonio Lubrano, Ennio Picerno, Valentina Padula, Angela Anna D’Angelo, Salvatore |
author_facet | Carriero, Antonio Lubrano, Ennio Picerno, Valentina Padula, Angela Anna D’Angelo, Salvatore |
author_sort | Carriero, Antonio |
collection | PubMed |
description | Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients. |
format | Online Article Text |
id | pubmed-8404638 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-84046382021-08-31 Corticosteroid injection treatment for dactylitis in psoriatic arthritis Carriero, Antonio Lubrano, Ennio Picerno, Valentina Padula, Angela Anna D’Angelo, Salvatore Ther Adv Musculoskelet Dis Intra-articular Treatment Options in the Management of Joint Disorders Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients. SAGE Publications 2021-08-28 /pmc/articles/PMC8404638/ /pubmed/34471429 http://dx.doi.org/10.1177/1759720X211041864 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Intra-articular Treatment Options in the Management of Joint Disorders Carriero, Antonio Lubrano, Ennio Picerno, Valentina Padula, Angela Anna D’Angelo, Salvatore Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title | Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title_full | Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title_fullStr | Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title_full_unstemmed | Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title_short | Corticosteroid injection treatment for dactylitis in psoriatic arthritis |
title_sort | corticosteroid injection treatment for dactylitis in psoriatic arthritis |
topic | Intra-articular Treatment Options in the Management of Joint Disorders |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404638/ https://www.ncbi.nlm.nih.gov/pubmed/34471429 http://dx.doi.org/10.1177/1759720X211041864 |
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