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Corticosteroid injection treatment for dactylitis in psoriatic arthritis

Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for...

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Autores principales: Carriero, Antonio, Lubrano, Ennio, Picerno, Valentina, Padula, Angela Anna, D’Angelo, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404638/
https://www.ncbi.nlm.nih.gov/pubmed/34471429
http://dx.doi.org/10.1177/1759720X211041864
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author Carriero, Antonio
Lubrano, Ennio
Picerno, Valentina
Padula, Angela Anna
D’Angelo, Salvatore
author_facet Carriero, Antonio
Lubrano, Ennio
Picerno, Valentina
Padula, Angela Anna
D’Angelo, Salvatore
author_sort Carriero, Antonio
collection PubMed
description Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients.
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spelling pubmed-84046382021-08-31 Corticosteroid injection treatment for dactylitis in psoriatic arthritis Carriero, Antonio Lubrano, Ennio Picerno, Valentina Padula, Angela Anna D’Angelo, Salvatore Ther Adv Musculoskelet Dis Intra-articular Treatment Options in the Management of Joint Disorders Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients. SAGE Publications 2021-08-28 /pmc/articles/PMC8404638/ /pubmed/34471429 http://dx.doi.org/10.1177/1759720X211041864 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Intra-articular Treatment Options in the Management of Joint Disorders
Carriero, Antonio
Lubrano, Ennio
Picerno, Valentina
Padula, Angela Anna
D’Angelo, Salvatore
Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title_full Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title_fullStr Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title_full_unstemmed Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title_short Corticosteroid injection treatment for dactylitis in psoriatic arthritis
title_sort corticosteroid injection treatment for dactylitis in psoriatic arthritis
topic Intra-articular Treatment Options in the Management of Joint Disorders
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404638/
https://www.ncbi.nlm.nih.gov/pubmed/34471429
http://dx.doi.org/10.1177/1759720X211041864
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