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Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

People infected with HIV (PWH) are highly susceptible to striatal and hippocampal damage. Motor and memory impairments are common among these patients, likely as behavioral manifestations of damage to these brain regions. GABAergic dysfunction from HIV infection and viral proteins such as transactiv...

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Detalles Bibliográficos
Autores principales: Barbour, Aaron J., Nass, Sara R., Hahn, Yun K., Hauser, Kurt F., Knapp, Pamela E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404672/
https://www.ncbi.nlm.nih.gov/pubmed/34445881
http://dx.doi.org/10.1177/17590914211022089

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