Binding and entering: COVID finds a new home

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In t...

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Detalles Bibliográficos
Autores principales: Vu, Michelle N., Menachery, Vineet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Pearls
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404997/
https://www.ncbi.nlm.nih.gov/pubmed/34460863
http://dx.doi.org/10.1371/journal.ppat.1009857
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author Vu, Michelle N.
Menachery, Vineet D.
author_facet Vu, Michelle N.
Menachery, Vineet D.
author_sort Vu, Michelle N.
collection PubMed
description Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus.
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spelling pubmed-84049972021-08-31 Binding and entering: COVID finds a new home Vu, Michelle N. Menachery, Vineet D. PLoS Pathog Pearls Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus. Public Library of Science 2021-08-30 /pmc/articles/PMC8404997/ /pubmed/34460863 http://dx.doi.org/10.1371/journal.ppat.1009857 Text en © 2021 Vu, Menachery https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pearls
Vu, Michelle N.
Menachery, Vineet D.
Binding and entering: COVID finds a new home
title Binding and entering: COVID finds a new home
title_full Binding and entering: COVID finds a new home
title_fullStr Binding and entering: COVID finds a new home
title_full_unstemmed Binding and entering: COVID finds a new home
title_short Binding and entering: COVID finds a new home
title_sort binding and entering: covid finds a new home
topic Pearls
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404997/
https://www.ncbi.nlm.nih.gov/pubmed/34460863
http://dx.doi.org/10.1371/journal.ppat.1009857
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