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Impact of HLA type, age and chronic viral infection on peripheral T-cell receptor sharing between unrelated individuals

The human adaptive immune system must generate extraordinary diversity to be able to respond to all possible pathogens. The T-cell repertoire derives this high diversity through somatic recombination of the T-cell receptor (TCR) locus, a random process that results in repertoires that are largely pr...

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Detalles Bibliográficos
Autores principales:	Johnson, Sarah A., Seale, Spencer L., Gittelman, Rachel M., Rytlewski, Julie A., Robins, Harlan S., Fields, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405014/ https://www.ncbi.nlm.nih.gov/pubmed/34460826 http://dx.doi.org/10.1371/journal.pone.0249484

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