A hidden Markov model reliably characterizes ketamine-induced spectral dynamics in macaque local field potentials and human electroencephalograms

Ketamine is an NMDA receptor antagonist commonly used to maintain general anesthesia. At anesthetic doses, ketamine causes high power gamma (25-50 Hz) oscillations alternating with slow-delta (0.1-4 Hz) oscillations. These dynamics are readily observed in local field potentials (LFPs) of non-human p...

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Detalles Bibliográficos
Autores principales: Garwood, Indie C., Chakravarty, Sourish, Donoghue, Jacob, Mahnke, Meredith, Kahali, Pegah, Chamadia, Shubham, Akeju, Oluwaseun, Miller, Earl K., Brown, Emery N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405019/
https://www.ncbi.nlm.nih.gov/pubmed/34407069
http://dx.doi.org/10.1371/journal.pcbi.1009280

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