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The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review
The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamp...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405129/ https://www.ncbi.nlm.nih.gov/pubmed/34476291 http://dx.doi.org/10.1097/TXD.0000000000001200 |
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author | Vetrugno, Luigi Cherchi, Vittorio Lorenzin, Dario De Lorenzo, Francesco Ventin, Marco Zanini, Victor Terrosu, Giovanni Risaliti, Andrea Baccarani, Umberto Bove, Tiziana |
author_facet | Vetrugno, Luigi Cherchi, Vittorio Lorenzin, Dario De Lorenzo, Francesco Ventin, Marco Zanini, Victor Terrosu, Giovanni Risaliti, Andrea Baccarani, Umberto Bove, Tiziana |
author_sort | Vetrugno, Luigi |
collection | PubMed |
description | The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamping, and reperfusion could also contribute to clot formation. The incidence of intracardiac thrombi formation stands at 4.2%, associated with a mortality rate of 45.5%, and to date, no consensus exists regarding the best way to treat this complication. Intraoperative transesophageal echocardiography is the only effective method for diagnosing intracardiac thrombi formation early, while point-of-care coagulation testing could guide the coagulation management potentially improving patient outcomes. |
format | Online Article Text |
id | pubmed-8405129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-84051292021-09-01 The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review Vetrugno, Luigi Cherchi, Vittorio Lorenzin, Dario De Lorenzo, Francesco Ventin, Marco Zanini, Victor Terrosu, Giovanni Risaliti, Andrea Baccarani, Umberto Bove, Tiziana Transplant Direct Liver Transplantation The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamping, and reperfusion could also contribute to clot formation. The incidence of intracardiac thrombi formation stands at 4.2%, associated with a mortality rate of 45.5%, and to date, no consensus exists regarding the best way to treat this complication. Intraoperative transesophageal echocardiography is the only effective method for diagnosing intracardiac thrombi formation early, while point-of-care coagulation testing could guide the coagulation management potentially improving patient outcomes. Lippincott Williams & Wilkins 2021-08-26 /pmc/articles/PMC8405129/ /pubmed/34476291 http://dx.doi.org/10.1097/TXD.0000000000001200 Text en Copyright © 2021 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Liver Transplantation Vetrugno, Luigi Cherchi, Vittorio Lorenzin, Dario De Lorenzo, Francesco Ventin, Marco Zanini, Victor Terrosu, Giovanni Risaliti, Andrea Baccarani, Umberto Bove, Tiziana The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title | The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title_full | The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title_fullStr | The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title_full_unstemmed | The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title_short | The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review |
title_sort | challenging management of an intracardiac thrombus in a liver transplant patient at the reperfusion phase: a case report and brief literature review |
topic | Liver Transplantation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405129/ https://www.ncbi.nlm.nih.gov/pubmed/34476291 http://dx.doi.org/10.1097/TXD.0000000000001200 |
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