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Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation

Our previous study showed that growth arrest- and DNA damage-inducible gene 153 (GAD153/CHOP) plays an important role in intermittent hypoxia- (IH-) induced apoptosis and impaired synaptic plasticity. This study is aimed at determining which signaling pathway is activated to induce CHOP and the role...

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Detalles Bibliográficos
Autores principales:	Xu, Linhao, Bi, Yanli, Xu, Yizhou, Wu, Yihao, Du, Xiaoxue, Mou, Yixuan, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405296/ https://www.ncbi.nlm.nih.gov/pubmed/34471408 http://dx.doi.org/10.1155/2021/4090441

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