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Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405324/ https://www.ncbi.nlm.nih.gov/pubmed/34471461 http://dx.doi.org/10.1155/2021/1131280 |
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author | Cruz-Martins, Natália Quispe, Cristina Kırkın, Celale Şenol, Ezgi Zuluğ, Aslı Özçelik, Beraat Ademiluyi, Adedayo O. Oyeniran, Olubukola Helen Semwal, Prabhakar Kumar, Manoj Sharopov, Farukh López, Victor Les, Francisco Bagiu, Iulia-Cristina Butnariu, Monica Sharifi-Rad, Javad Alshehri, Mohammed M. Cho, William C. |
author_facet | Cruz-Martins, Natália Quispe, Cristina Kırkın, Celale Şenol, Ezgi Zuluğ, Aslı Özçelik, Beraat Ademiluyi, Adedayo O. Oyeniran, Olubukola Helen Semwal, Prabhakar Kumar, Manoj Sharopov, Farukh López, Victor Les, Francisco Bagiu, Iulia-Cristina Butnariu, Monica Sharifi-Rad, Javad Alshehri, Mohammed M. Cho, William C. |
author_sort | Cruz-Martins, Natália |
collection | PubMed |
description | Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules. |
format | Online Article Text |
id | pubmed-8405324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-84053242021-08-31 Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder Cruz-Martins, Natália Quispe, Cristina Kırkın, Celale Şenol, Ezgi Zuluğ, Aslı Özçelik, Beraat Ademiluyi, Adedayo O. Oyeniran, Olubukola Helen Semwal, Prabhakar Kumar, Manoj Sharopov, Farukh López, Victor Les, Francisco Bagiu, Iulia-Cristina Butnariu, Monica Sharifi-Rad, Javad Alshehri, Mohammed M. Cho, William C. Oxid Med Cell Longev Review Article Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules. Hindawi 2021-08-21 /pmc/articles/PMC8405324/ /pubmed/34471461 http://dx.doi.org/10.1155/2021/1131280 Text en Copyright © 2021 Natália Cruz-Martins et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cruz-Martins, Natália Quispe, Cristina Kırkın, Celale Şenol, Ezgi Zuluğ, Aslı Özçelik, Beraat Ademiluyi, Adedayo O. Oyeniran, Olubukola Helen Semwal, Prabhakar Kumar, Manoj Sharopov, Farukh López, Victor Les, Francisco Bagiu, Iulia-Cristina Butnariu, Monica Sharifi-Rad, Javad Alshehri, Mohammed M. Cho, William C. Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title | Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_full | Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_fullStr | Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_full_unstemmed | Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_short | Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_sort | paving plant-food-derived bioactives as effective therapeutic agents in autism spectrum disorder |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405324/ https://www.ncbi.nlm.nih.gov/pubmed/34471461 http://dx.doi.org/10.1155/2021/1131280 |
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