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Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors

Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicina...

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Autores principales: Gao, Shenghua, Huang, Tianguang, Song, Letian, Xu, Shujing, Cheng, Yusen, Cherukupalli, Srinivasulu, Kang, Dongwei, Zhao, Tong, Sun, Lin, Zhang, Jian, Zhan, Peng, Liu, Xinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405450/
https://www.ncbi.nlm.nih.gov/pubmed/34485029
http://dx.doi.org/10.1016/j.apsb.2021.08.027
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author Gao, Shenghua
Huang, Tianguang
Song, Letian
Xu, Shujing
Cheng, Yusen
Cherukupalli, Srinivasulu
Kang, Dongwei
Zhao, Tong
Sun, Lin
Zhang, Jian
Zhan, Peng
Liu, Xinyong
author_facet Gao, Shenghua
Huang, Tianguang
Song, Letian
Xu, Shujing
Cheng, Yusen
Cherukupalli, Srinivasulu
Kang, Dongwei
Zhao, Tong
Sun, Lin
Zhang, Jian
Zhan, Peng
Liu, Xinyong
author_sort Gao, Shenghua
collection PubMed
description Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective.
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spelling pubmed-84054502021-08-31 Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors Gao, Shenghua Huang, Tianguang Song, Letian Xu, Shujing Cheng, Yusen Cherukupalli, Srinivasulu Kang, Dongwei Zhao, Tong Sun, Lin Zhang, Jian Zhan, Peng Liu, Xinyong Acta Pharm Sin B Review Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective. Elsevier 2022-02 2021-08-31 /pmc/articles/PMC8405450/ /pubmed/34485029 http://dx.doi.org/10.1016/j.apsb.2021.08.027 Text en © 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Gao, Shenghua
Huang, Tianguang
Song, Letian
Xu, Shujing
Cheng, Yusen
Cherukupalli, Srinivasulu
Kang, Dongwei
Zhao, Tong
Sun, Lin
Zhang, Jian
Zhan, Peng
Liu, Xinyong
Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title_full Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title_fullStr Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title_full_unstemmed Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title_short Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
title_sort medicinal chemistry strategies towards the development of effective sars-cov-2 inhibitors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405450/
https://www.ncbi.nlm.nih.gov/pubmed/34485029
http://dx.doi.org/10.1016/j.apsb.2021.08.027
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