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A latent variable approach to account for correlated inputs in global sensitivity analysis
In drug development decision-making is often supported through model-based methods, such as physiologically-based pharmacokinetics (PBPK). Global sensitivity analysis (GSA) is gaining use for quality assessment of model-informed inference. However, the inclusion and interpretation of correlated fact...
Autores principales: | Melillo, Nicola, Darwich, Adam S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405496/ https://www.ncbi.nlm.nih.gov/pubmed/34032996 http://dx.doi.org/10.1007/s10928-021-09764-x |
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