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Impact of the COVID-19 pandemic in patients with systemic lupus erythematosus throughout one year

Little is known about the impact of coronavirus disease 2019 (COVID-19) pandemic to the care of patients with systemic lupus erythematosus (SLE) in the long-term. By crossing population data with the results of a web-based survey focused on the timeframes January–April and May–December 2020, we foun...

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Detalles Bibliográficos
Autores principales: Ramirez, Giuseppe A., Argolini, Lorenza M., Bellocchi, Chiara, Moroni, Luca, Della-Torre, Emanuel, Farina, Nicola, Caporali, Roberto F., Beretta, Lorenzo, Gerosa, Maria, Bozzolo, Enrica P., Dagna, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405598/
https://www.ncbi.nlm.nih.gov/pubmed/34478882
http://dx.doi.org/10.1016/j.clim.2021.108845
Descripción
Sumario:Little is known about the impact of coronavirus disease 2019 (COVID-19) pandemic to the care of patients with systemic lupus erythematosus (SLE) in the long-term. By crossing population data with the results of a web-based survey focused on the timeframes January–April and May–December 2020, we found that among 334/518 responders, 28 had COVID-19 in 2020. Seventeen cases occurred in May–December, in parallel with trends in the general population and loosening of containment policy strength. Age > 40 years (p = 0.026), prednisone escalation (p = 0.008) and infected relatives (p < 0.001) were most significantly associated with COVID-19. Weaker associations were found with asthma, lymphadenopathy and azathioprine or cyclosporine treatment. Only 31% of patients with infected relatives developed COVID-19. Healthcare service disruptions were not associated with rising hospitalisations. Vaccination prospects were generally welcomed. Our data suggest that COVID-19 has a moderate impact on patients with SLE, which might be significantly modulated by public health policies, including vaccination.