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CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1

Failures to treat triple-negative breast cancer (TNBC) are mainly due to chemoresistance or radioresistance. We and others previously discovered that zinc finger E-box-binding homeobox 1 (ZEB1) is a massive driver causing these resistance. However, how to dynamically modulate the intrinsic expressio...

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Detalles Bibliográficos
Autores principales: Luo, Hong, Zhou, Zhicheng, Huang, Shan, Ma, Mengru, Zhao, Manyu, Tang, Lixu, Quan, Yuan, Zeng, Yiming, Su, Li, Kim, Jongchan, Zhang, Peijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405615/
https://www.ncbi.nlm.nih.gov/pubmed/34462429
http://dx.doi.org/10.1038/s41419-021-04114-8