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The reproductive success of bovine sperm after sex-sorting: a meta-analysis
In the three decades since its inception, the sex-sorting technology has progressed significantly. However, field studies report conflicting findings regarding reproductive outcomes. Therefore, we conducted this meta-analysis of all trials published between 1999 and 2021. Non-return rates after 24 o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405645/ https://www.ncbi.nlm.nih.gov/pubmed/34462506 http://dx.doi.org/10.1038/s41598-021-96834-2 |
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author | Reese, Sven Pirez, Miguel Camara Steele, Heather Kölle, Sabine |
author_facet | Reese, Sven Pirez, Miguel Camara Steele, Heather Kölle, Sabine |
author_sort | Reese, Sven |
collection | PubMed |
description | In the three decades since its inception, the sex-sorting technology has progressed significantly. However, field studies report conflicting findings regarding reproductive outcomes. Therefore, we conducted this meta-analysis of all trials published between 1999 and 2021. Non-return rates after 24 or 60 d (NRR 24/60), pregnancy, calving, abortion, and stillbirth rates were compared after AI with sex-sorted vs non-sorted sperm. Additionally, the impact of recent developments in the sex-sorting technology was assessed. Of 860 studies found, 45 studies (72 trials) provided extractable data and were included. Overall, the results of this meta-analysis provided evidence that the NRR 24/60 was diminished by 13%, pregnancy rates were reduced by 23% (25% cows, 21% heifers) and calving rates were reduced by 24% when using sex-sorted sperm. Enhancing the dosage to 4 million sex-sorted sperm/straw (including recent improvements, high vs low dose) as well as using fresh sex-sorted sperm (sorted vs non-sorted) increased pregnancy rate ratios by 7 percentage points. The refinement of the sex-sorting technology after 2015 resulted in a lowered reduction of pregnancy and calving rate of 19% and 23%, respectively. Whereas abortion rates were similar, the stillbirth of male calves was increased by 6.3%. |
format | Online Article Text |
id | pubmed-8405645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84056452021-09-01 The reproductive success of bovine sperm after sex-sorting: a meta-analysis Reese, Sven Pirez, Miguel Camara Steele, Heather Kölle, Sabine Sci Rep Article In the three decades since its inception, the sex-sorting technology has progressed significantly. However, field studies report conflicting findings regarding reproductive outcomes. Therefore, we conducted this meta-analysis of all trials published between 1999 and 2021. Non-return rates after 24 or 60 d (NRR 24/60), pregnancy, calving, abortion, and stillbirth rates were compared after AI with sex-sorted vs non-sorted sperm. Additionally, the impact of recent developments in the sex-sorting technology was assessed. Of 860 studies found, 45 studies (72 trials) provided extractable data and were included. Overall, the results of this meta-analysis provided evidence that the NRR 24/60 was diminished by 13%, pregnancy rates were reduced by 23% (25% cows, 21% heifers) and calving rates were reduced by 24% when using sex-sorted sperm. Enhancing the dosage to 4 million sex-sorted sperm/straw (including recent improvements, high vs low dose) as well as using fresh sex-sorted sperm (sorted vs non-sorted) increased pregnancy rate ratios by 7 percentage points. The refinement of the sex-sorting technology after 2015 resulted in a lowered reduction of pregnancy and calving rate of 19% and 23%, respectively. Whereas abortion rates were similar, the stillbirth of male calves was increased by 6.3%. Nature Publishing Group UK 2021-08-30 /pmc/articles/PMC8405645/ /pubmed/34462506 http://dx.doi.org/10.1038/s41598-021-96834-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Reese, Sven Pirez, Miguel Camara Steele, Heather Kölle, Sabine The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title | The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title_full | The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title_fullStr | The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title_full_unstemmed | The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title_short | The reproductive success of bovine sperm after sex-sorting: a meta-analysis |
title_sort | reproductive success of bovine sperm after sex-sorting: a meta-analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405645/ https://www.ncbi.nlm.nih.gov/pubmed/34462506 http://dx.doi.org/10.1038/s41598-021-96834-2 |
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