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Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems

Advanced glycation endproducts (AGEs) are involved in several diseases, including NAFLD and NASH. RAGE is the main receptor mediating the pro-inflammatory signalling induced by AGEs. Therefore, targeting of RAGE has been proposed for prevention of chronic inflammatory diseases. However, the role of...

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Detalles Bibliográficos
Autores principales:	Wouters, Kristiaan, Cento, Alessia S., Gaens, Katrien H., Teunissen, Margee, Scheijen, Jean L. J. M., Barutta, Federica, Chiazza, Fausto, Collotta, Debora, Aragno, Manuela, Gruden, Gabriella, Collino, Massimo, Schalkwijk, Casper G., Mastrocola, Raffaella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405685/ https://www.ncbi.nlm.nih.gov/pubmed/34462492 http://dx.doi.org/10.1038/s41598-021-96859-7

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