VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance

Radiotherapy remains the mainstay for treatment of various types of human cancer; however, the clinical efficacy is often limited by radioresistance, in which the underlying mechanism is largely unknown. Here, using esophageal squamous cell carcinoma (ESCC) as a model, we demonstrate that guanine nu...

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Detalles Bibliográficos
Autores principales: Liu, Weiling, Miao, Chuanwang, Zhang, Shaosen, Liu, Yachen, Niu, Xiangjie, Xi, Yiyi, Guo, Wenjia, Chu, Jiahui, Lin, Ai, Liu, Hongjin, Yang, Xinyu, Chen, Xinjie, Zhong, Ce, Ma, Yuling, Wang, Yuqian, Zhu, Shihao, Liu, Shuning, Tan, Wen, Lin, Dongxin, Wu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405816/
https://www.ncbi.nlm.nih.gov/pubmed/34462423
http://dx.doi.org/10.1038/s41392-021-00735-9

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