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Mammalian acetate-dependent acetyl CoA synthetase 2 contains multiple protein destabilization and masking elements

Besides contributing to anabolism, cellular metabolites serve as substrates or cofactors for enzymes and may also have signaling functions. Given these roles, multiple control mechanisms likely ensure fidelity of metabolite-generating enzymes. Acetate-dependent acetyl CoA synthetases (ACS) are de no...

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Detalles Bibliográficos
Autores principales:	Nagati, Jason S., Kobeissy, Philippe H., Nguyen, Minh Q., Xu, Min, Garcia, Trent, Comerford, Sarah A., Hammer, Robert E., Garcia, Joseph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405932/ https://www.ncbi.nlm.nih.gov/pubmed/34343565 http://dx.doi.org/10.1016/j.jbc.2021.101037

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