POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1

Fibrillin-1 (FBN1) is the major component of extracellular matrix microfibrils, which are required for proper development of elastic tissues, including the heart and lungs. Through protein–protein interactions with latent transforming growth factor (TGF) β-binding protein 1 (LTBP1), microfibrils reg...

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Detalles Bibliográficos
Autores principales: Williamson, Daniel B., Sohn, Camron J., Ito, Atsuko, Haltiwanger, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405936/
https://www.ncbi.nlm.nih.gov/pubmed/34411563
http://dx.doi.org/10.1016/j.jbc.2021.101055

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