Blocking GRP/GRP-R signaling decreases expression of androgen receptor splice variants and inhibits tumor growth in castration-resistant prostate cancer

Clinical management of castration-resistant prostate cancer (CRPC) resulting from androgen deprivation therapy (ADT) remains challenging. Many studies indicate that androgen receptor splice variants (ARVs) play a critical role in the development of CRPC, including resistance to the new generation of...

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Detalles Bibliográficos
Autores principales: Case, Thomas C., Merkel, Alyssa, Ramirez-Solano, Marisol, Liu, Qi, Sterling, Julie A., Jin, Renjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405941/
https://www.ncbi.nlm.nih.gov/pubmed/34461557
http://dx.doi.org/10.1016/j.tranon.2021.101213

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