Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology and high actomyosin contractility driven by Rho GTPase sig...

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Detalles Bibliográficos
Autores principales: de Winde, Charlotte M., George, Samantha L., Crosas-Molist, Eva, Hari-Gupta, Yukti, Arp, Abbey B., Benjamin, Agnesska C., Millward, Lindsey J., Makris, Spyridon, Carver, Alexander, Imperatore, Valerio, Martínez, Víctor G., Sanz-Moreno, Victoria, Acton, Sophie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405990/
https://www.ncbi.nlm.nih.gov/pubmed/34485858
http://dx.doi.org/10.1016/j.isci.2021.102976

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