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A novel recognition site for polyubiquitin and ubiquitin-like signals in an unexpected region of proteasomal subunit Rpn1

The ubiquitin (Ub)–proteasome system is the primary mechanism for maintaining protein homeostasis in eukaryotes, yet the underlying signaling events and specificities of its components are poorly understood. Proteins destined for degradation are tagged with covalently linked polymeric Ub chains and...

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Detalles Bibliográficos
Autores principales: Boughton, Andrew J., Liu, Leonard, Lavy, Tali, Kleifeld, Oded, Fushman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405992/
https://www.ncbi.nlm.nih.gov/pubmed/34364874
http://dx.doi.org/10.1016/j.jbc.2021.101052

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