A protocol for high-throughput screening of histone lysine demethylase 4 inhibitors using TR-FRET assay

Identification of diverse chemotypes of selective KDM4 inhibitors is important for exploring and validating the roles of KDM4s in the pathogenesis of human disease and for developing therapies. Here, we report a protocol for high-throughput screening of KDM4 inhibitors using TR-FRET demethylation fu...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Lin, Wenwei, Li, Zhen-Mei, Rankovic, Zoran, White, Stephen W., Chen, Taosheng, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406026/
https://www.ncbi.nlm.nih.gov/pubmed/34485934
http://dx.doi.org/10.1016/j.xpro.2021.100702

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