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Serine/threonine ligation-assisted chemical synthesis of HMGA1a protein with site-specific post-translational modifications
Dissecting the function of proteins’ post-translational modifications (PTMs) is seriously hindered by the difficulty in obtaining the homogeneous protein with the PTMs of interest. Chemical protein synthesis offers a great potential to overcome this limitation. Here, a detailed protocol is introduce...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406030/ https://www.ncbi.nlm.nih.gov/pubmed/34485943 http://dx.doi.org/10.1016/j.xpro.2021.100777 |