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Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

Natural products that possess alkyne or polyyne moieties have been isolated from a variety of biological sources and possess a broad a range of bioactivities. In bacteria, the basic biosynthesis of polyynes is known, but their biosynthetic gene cluster (BGC) distribution and evolutionary relationshi...

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Detalles Bibliográficos
Autores principales:	Mullins, Alex J., Webster, Gordon, Kim, Hak Joong, Zhao, Jinlian, Petrova, Yoana D., Ramming, Christina E., Jenner, Matthew, Murray, James A. H., Connor, Thomas R., Hertweck, Christian, Challis, Gregory L., Mahenthiralingam, Eshwar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406139/ https://www.ncbi.nlm.nih.gov/pubmed/34340549 http://dx.doi.org/10.1128/mBio.00715-21

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