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UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat

HIV-1 remains incurable due to viral reservoirs, which lead to durably latent HIV infection. Identifying novel host factors and deciphering the molecular mechanisms involved in the establishment and maintenance of latency are critical to discover new targets for the development of novel anti-HIV age...

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Detalles Bibliográficos
Autores principales:	Liang, Taizhen, Zhang, Qiao, Wu, Ziyao, Chen, Pei, Huang, Yifan, Liu, Shuwen, Li, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406157/ https://www.ncbi.nlm.nih.gov/pubmed/34465029 http://dx.doi.org/10.1128/mBio.01625-21

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