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Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype

Ebola virus (EBOV) VP24 protein is a nucleocapsid-associated protein that inhibits interferon (IFN) gene expression and counteracts the IFN-mediated antiviral response, preventing nuclear import of signal transducer and activator of transcription 1 (STAT1). Proteomic studies to identify additional E...

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Detalles Bibliográficos
Autores principales: Vidal, Santiago, Sánchez-Aparicio, Maite, Seoane, Rocío, El Motiam, Ahmed, Nelson, Emily V., Bouzaher, Yanis H., Baz-Martínez, Maite, García-Dorival, Isabel, Gonzalo, Susana, Vázquez, Enrique, Vidal, Anxo, Muñoz-Fontela, César, García-Sastre, Adolfo, Rivas, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406168/
https://www.ncbi.nlm.nih.gov/pubmed/34225493
http://dx.doi.org/10.1128/mBio.00972-21