Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness

Despite our extensive knowledge of the genetic regulation of heat shock proteins (HSPs), the evolutionary routes that allow bacteria to adaptively tune their HSP levels and corresponding proteostatic robustness have been explored less. In this report, directed evolution experiments using the Escheri...

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Detalles Bibliográficos
Autores principales: Mortier, Julien, Gayán, Elisa, Van Eyken, Ronald, Torres Montaguth, Oscar Enrique, Khodaparast, Ladan, Khodaparast, Laleh, Houben, Bert, Carpentier, Sebastien, Rousseau, Frederic, Schymkowitz, Joost, Aertsen, Abram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406189/
https://www.ncbi.nlm.nih.gov/pubmed/34225482
http://dx.doi.org/10.1128/mBio.01129-21

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