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HIV-1 Vpu Promotes Phagocytosis of Infected CD4(+) T Cells by Macrophages through Downregulation of CD47

Human immunodeficiency virus (HIV) remodels the cell surface of infected cells to facilitate viral dissemination and promote immune evasion. The membrane-associated viral protein U (Vpu) accessory protein encoded by HIV-1 plays a key role in this process by altering cell surface levels of multiple h...

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Detalles Bibliográficos
Autores principales:	Cong, Lijun, Sugden, Scott M., Leclair, Pascal, Lim, Chinten James, Pham, Tram N. Q., Cohen, Éric A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406190/ https://www.ncbi.nlm.nih.gov/pubmed/34425695 http://dx.doi.org/10.1128/mBio.01920-21

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