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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication. The main protease (M(pro)), encoded as part of two polyproteins, pp1a and pp1ab, is responsible for 11 different cleavages of the...

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Detalles Bibliográficos
Autores principales:	Davis, David A., Bulut, Haydar, Shrestha, Prabha, Yaparla, Amulya, Jaeger, Hannah K., Hattori, Shin-ichiro, Wingfield, Paul T., Mieyal, John J., Mitsuya, Hiroaki, Yarchoan, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406260/ https://www.ncbi.nlm.nih.gov/pubmed/34399606 http://dx.doi.org/10.1128/mBio.02094-21

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