Cargando…

Inactivation of Transcriptional Regulator FabT Influences Colony Phase Variation of Streptococcus pneumoniae

Streptococcus pneumoniae is an opportunistic pathogen that can alter its cell surface phenotype in response to the host environment. We demonstrated that the transcriptional regulator FabT is an indirect regulator of capsular polysaccharide, an important virulence factor of Streptococcus pneumoniae....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jinghui, Ye, Weijie, Wu, Kaifeng, Xiao, Shengnan, Zheng, Yuqiang, Shu, Zhaoche, Yin, Yibing, Zhang, Xuemei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406281/ https://www.ncbi.nlm.nih.gov/pubmed/34399624 http://dx.doi.org/10.1128/mBio.01304-21

Ejemplares similares

The Response Regulator YycF Inhibits Expression of the Fatty Acid Biosynthesis Repressor FabT in Streptococcus pneumoniae
por: Mohedano, Maria L., et al.
Publicado: (2016)

Pneumococcal LytR Protein Is Required for the Surface Attachment of Both Capsular Polysaccharide and Teichoic Acids: Essential for Pneumococcal Virulence
por: Ye, Weijie, et al.
Publicado: (2018)

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids
por: Zou, Qi, et al.
Publicado: (2022)

MgaSpn is a negative regulator of capsule and phosphorylcholine biosynthesis and influences the virulence of Streptococcus pneumoniae D39
por: Xiao, Shengnan, et al.
Publicado: (2021)

Streptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner
por: Shu, Zhaoche, et al.
Publicado: (2020)

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation
por: Li, Sijie, et al.
Publicado: (2020)

CpsR, a GntR family regulator, transcriptionally regulates capsular polysaccharide biosynthesis and governs bacterial virulence in Streptococcus pneumoniae
por: Wu, Kaifeng, et al.
Publicado: (2016)

ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae
por: Zheng, Yuqiang, et al.
Publicado: (2017)

comCDE (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39
por: Zhang, Yapeng, et al.
Publicado: (2023)

Discovery of novel inhibitors of Streptococcus pneumoniae based on the virtual screening with the homology-modeled structure of histidine kinase (VicK)
por: Li, Nan, et al.
Publicado: (2009)

IL-6 During Influenza-Streptococcus pneumoniae Co-Infected Pneumonia—A Protector
por: Gou, Xuemei, et al.
Publicado: (2020)

Screening and Identification of DnaJ Interaction Proteins in Streptococcus pneumoniae
por: Cai, YingYing, et al.
Publicado: (2013)

Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer
por: Zhang, Hong, et al.
Publicado: (2020)

Antibacterial effects of Traditional Chinese Medicine monomers against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK)
por: Zhang, Shuai, et al.
Publicado: (2015)

Single chain Fab (scFab) fragment
por: Hust, Michael, et al.
Publicado: (2007)

Frequent Beneficial Mutations during Single-Colony Serial Transfer of Streptococcus pneumoniae
por: Stevens, Kathleen E., et al.
Publicado: (2011)

Characterization of Human Colorectal Cancer MDR1/P-gp Fab Antibody
por: Zhang, Xuemei, et al.
Publicado: (2013)

Erratum to “Characterization of Human Colorectal Cancer MDR1/P-gp Fab Antibody”
por: Zhang, Xuemei, et al.
Publicado: (2014)

Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood–brain barrier and target glioma
por: Ji, Xuemei, et al.
Publicado: (2019)

Allelic Variation of the Capsule Promoter Diversifies Encapsulation and Virulence In Streptococcus pneumoniae
por: Wen, Zhensong, et al.
Publicado: (2016)

Production of single chain Fab (scFab) fragments in Bacillus megaterium
por: Jordan, Eva, et al.
Publicado: (2007)

Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways
por: Zhang, Hong, et al.
Publicado: (2016)

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae
por: Li, Jing, et al.
Publicado: (2016)

Effect of inactivated Streptococcus pneumoniae as non-pathogenic particles on the severity of pneumonia caused by respiratory syncytial virus infection in mice
por: Miyauchi, Aki, et al.
Publicado: (2019)

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
por: Beckmann, Roland, et al.
Publicado: (2021)

Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection
por: Zhang, Xinyuan, et al.
Publicado: (2018)

Fab : the coming revolution on your desktop--from personal computers to personal fabrication
por: Gershenfeld, Neil A.
Publicado: (2005)

Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis
por: Zhu, Lei, et al.
Publicado: (2009)

FabR regulates Salmonella biofilm formation via its direct target FabB
por: Hermans, Kim, et al.
Publicado: (2016)

Pneumonia and Streptococcus pneumoniae vaccine
por: Kim, Gyu-Lee, et al.
Publicado: (2017)

The Inactivation of a New Peptidoglycan Hydrolase Pmp23 Leads to Abnormal Septum Formation in Streptococcus pneumoniae
por: E, Pagliero, et al.
Publicado: (2008)

Inactivation of the Rgg2 Transcriptional Regulator Ablates the Virulence of Streptococcus pyogenes
por: Zutkis, Anastasia A., et al.
Publicado: (2014)

Detoxified pneumolysin derivative ΔA146Ply inhibits autophagy and induces apoptosis in acute myeloid leukemia cells by activating mTOR signaling
por: Zhu, Tao, et al.
Publicado: (2022)

Stability enhancement in a mAb and Fab coformulation
por: Zhang, Hongyu, et al.
Publicado: (2020)

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates
por: Salter, S. J., et al.
Publicado: (2012)

Self-fab house : 2nd Advanced Architecture Contest /
Publicado: (2009)

Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis
por: Zhao, Shengnan, et al.
Publicado: (2020)

Fab-arm exchange is a misnomer
por: Pandey, Janardan P.
Publicado: (2012)

Meditope–Fab interaction: threading the hole
por: Bzymek, Krzysztof P., et al.
Publicado: (2017)

Ranking routes in semiconductor wafer fabs
por: Gupta, Shreya, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g96cdrtfvu0e8k98dg7ltghghq