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Ileal Bile Acid Transporter Inhibitor Improves Hepatic Steatosis by Ameliorating Gut Microbiota Dysbiosis in NAFLD Model Mice

Nonalcoholic fatty liver disease (NAFLD), characterized by excessive fat deposition in the liver unrelated to alcohol consumption, is highly prevalent worldwide. However, effective therapeutic agents approved for NAFLD treatment are lacking. An ileal bile acid transporter inhibitor (IBATi), which re...

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Detalles Bibliográficos
Autores principales: Matsui, Masahiro, Fukunishi, Shinya, Nakano, Takashi, Ueno, Takaaki, Higuchi, Kazuhide, Asai, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406289/
https://www.ncbi.nlm.nih.gov/pubmed/34225483
http://dx.doi.org/10.1128/mBio.01155-21