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Ileal Bile Acid Transporter Inhibitor Improves Hepatic Steatosis by Ameliorating Gut Microbiota Dysbiosis in NAFLD Model Mice
Nonalcoholic fatty liver disease (NAFLD), characterized by excessive fat deposition in the liver unrelated to alcohol consumption, is highly prevalent worldwide. However, effective therapeutic agents approved for NAFLD treatment are lacking. An ileal bile acid transporter inhibitor (IBATi), which re...
Autores principales: | Matsui, Masahiro, Fukunishi, Shinya, Nakano, Takashi, Ueno, Takaaki, Higuchi, Kazuhide, Asai, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406289/ https://www.ncbi.nlm.nih.gov/pubmed/34225483 http://dx.doi.org/10.1128/mBio.01155-21 |
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