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Reovirus Nonstructural Protein σNS Recruits Viral RNA to Replication Organelles

The function of the mammalian orthoreovirus (reovirus) σNS nonstructural protein is enigmatic. σNS is an RNA-binding protein that forms oligomers and enhances the stability of bound RNAs, but the mechanisms by which it contributes to reovirus replication are unknown. To determine the function of σNS...

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Detalles Bibliográficos
Autores principales: Lee, Christopher H., Raghunathan, Krishnan, Taylor, Gwen M., French, Andrea J., Tenorio, Raquel, Fernández de Castro, Isabel, Risco, Cristina, Parker, John S. L., Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406312/
https://www.ncbi.nlm.nih.gov/pubmed/34225484
http://dx.doi.org/10.1128/mBio.01408-21