Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response

The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20...

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Detalles Bibliográficos
Autor principal: Murphy, Eain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406314/
https://www.ncbi.nlm.nih.gov/pubmed/34425704
http://dx.doi.org/10.1128/mBio.00700-21
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author Murphy, Eain A.
author_facet Murphy, Eain A.
author_sort Murphy, Eain A.
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description The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.
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spelling pubmed-84063142021-09-09 Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response Murphy, Eain A. mBio Commentary The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon. American Society for Microbiology 2021-08-24 /pmc/articles/PMC8406314/ /pubmed/34425704 http://dx.doi.org/10.1128/mBio.00700-21 Text en Copyright © 2021 Murphy. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Murphy, Eain A.
Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_fullStr Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full_unstemmed Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_short Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_sort reevaluating the impact of epstein-barr virus noncoding rnas on the interferon response
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406314/
https://www.ncbi.nlm.nih.gov/pubmed/34425704
http://dx.doi.org/10.1128/mBio.00700-21
work_keys_str_mv AT murphyeaina reevaluatingtheimpactofepsteinbarrvirusnoncodingrnasontheinterferonresponse

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