Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine

Aspergillus fumigatus is an important fungal pathogen and the main etiological agent of aspergillosis, a disease characterized by a noninvasive process that can evolve to a more severe clinical manifestation, called invasive pulmonary aspergillosis (IPA), in immunocompromised patients. The antifunga...

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Detalles Bibliográficos
Autores principales: dos Reis, Thaila Fernanda, Horta, Maria Augusta Crivelente, Colabardini, Ana Cristina, Fernandes, Caroline Mota, Silva, Lilian Pereira, Bastos, Rafael Wesley, Fonseca, Maria Vitória de Lazari, Wang, Fang, Martins, Celso, Rodrigues, Márcio L., Silva Pereira, Cristina, Del Poeta, Maurizio, Wong, Koon Ho, Goldman, Gustavo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406317/
https://www.ncbi.nlm.nih.gov/pubmed/34372704
http://dx.doi.org/10.1128/mBio.01458-21

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