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Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation

Inflammasomes are cytosolic multiprotein signaling complexes that are activated upon pattern recognition receptor-mediated recognition of pathogen-derived ligands or endogenous danger signals. Their assembly activates the downstream inflammatory caspase-1 and caspase-4/5 (human) or caspase-11 (mouse...

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Detalles Bibliográficos
Autores principales:	Dilucca, Marisa, Ramos, Saray, Shkarina, Kateryna, Santos, José Carlos, Broz, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406320/ https://www.ncbi.nlm.nih.gov/pubmed/34399626 http://dx.doi.org/10.1128/mBio.02054-21

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