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Broadly Reactive IgG Responses to Heterologous H5 Prime-Boost Influenza Vaccination Are Shaped by Antigenic Relatedness to Priming Strains

Prime-boost vaccinations of humans with different H5 strains have generated broadly protective antibody levels. However, the effect of an individual’s H5 exposure history on antibody responses to subsequent H5 vaccination is poorly understood. To investigate this, we analyzed the IgG responses to H5...

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Detalles Bibliográficos
Autores principales: Wang, Jiong, Li, Dongmei, Perry, Sheldon, Hilchey, Shannon P., Wiltse, Alexander, Treanor, John J., Sangster, Mark Y., Zand, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406322/
https://www.ncbi.nlm.nih.gov/pubmed/34225490
http://dx.doi.org/10.1128/mBio.00449-21

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