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Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells

Zika virus (ZIKV) is a neurovirulent flavivirus that uniquely causes fetal microcephaly, is sexually transmitted, and persists in patients for up to 6 months. ZIKV persistently infects human brain microvascular endothelial cells (hBMECs) that form the blood-brain barrier (BBB) and enables viral spre...

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Detalles Bibliográficos
Autores principales: Mladinich, Megan C., Conde, Jonas N., Schutt, William R., Sohn, Sook-Young, Mackow, Erich R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406327/
https://www.ncbi.nlm.nih.gov/pubmed/34399621
http://dx.doi.org/10.1128/mBio.01962-21