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Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling

[Image: see text] Cyclotides are plant-derived disulfide-rich peptides comprising a cyclic cystine knot, which confers remarkable stability against thermal, proteolytic, and chemical degradation. They represent an emerging class of G protein-coupled receptor (GPCR) ligands. In this study, utilizing...

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Detalles Bibliográficos
Autores principales:	Muratspahić, Edin, Tomašević, Nataša, Nasrollahi-Shirazi, Shahrooz, Gattringer, Jasmin, Emser, Fabiola Susanna, Freissmuth, Michael, Gruber, Christian W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406418/ https://www.ncbi.nlm.nih.gov/pubmed/34308635 http://dx.doi.org/10.1021/acs.jnatprod.1c00301

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