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Spindle assembly checkpoint activation and silencing at kinetochores

The spindle assembly checkpoint (SAC) is a surveillance mechanism that promotes accurate chromosome segregation in mitosis. The checkpoint senses the attachment state of kinetochores, the proteinaceous structures that assemble onto chromosomes in mitosis in order to mediate their interaction with sp...

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Detalles Bibliográficos
Autores principales: Lara-Gonzalez, Pablo, Pines, Jonathon, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406419/
https://www.ncbi.nlm.nih.gov/pubmed/34210579
http://dx.doi.org/10.1016/j.semcdb.2021.06.009